Zepeda, will compete against Regis Prograis for the vacant WBC super lightweight championship.
Although Zepeda, 33, lost his first two championship bouts, neither loss was decisive.
In July 2015, during his contest with Terry Flanagan the La Puente sustained a separated shoulder.
Zepeda was unable to continue, so Flanagan (at the time 27-0) won the contest by technical knockout.
The winner of Zepeda vs. Prograis will be required to face Ramirez
(27-1, 17 KOs).
Zepeda (36-2, 28 KOs, 2 NC) will defend his world title against his hometown rival in his third matchup.
While Prograis (27-1, 23 KOs), a native of New Orleans, he is a resident of the greater Los Angeles area.
To be honest, I like it. I always fight in the backyard of my adversary," Zepeda said.
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