Benzema, 34,also helped Real Madrid won the Champions League and La Liga
Benzema was named the 2022 Ballon d'Or winner, given to the world's best player.
Didier Deschamps, the head coach, expressed his sadness for Karim, who he said "made this World Cup a huge ambition."
"In my life I never give up but tonight I have to think about the team like I always do," Benzema said.
Therefore, the reason urges me to turn over my position to someone who can help our team win the World Cup.
"The entire squad feels Karim's anguish and wishes him a speedy recovery," the French Football Federation stated.
According to the report, an MRI scan revealed the damage, which calls for "a three-week rehabilitation period."
In Group D, France has games against Australia on November 22, Denmark on November 26, and Tunisia on November 30.
Deschamps has suffered numerous significant player injuries and has to replace Benzema before Monday.
The 26-man roster's first roster omitted midfielders Paul Pogba and N'Golo Kante.
After being sidelined for Manchester United's last five games, defender Raphael Varane is working to get well.
Since the World Cup team was assembled last week, Saturday's workout was his first comprehensive one.
Ryan Garcia vs Gervonta Davis has been declared "done deal" for 2
023 by both boxers.